Seasonal variation of maternally derived respiratory syncytial virus antibodies and association with infant hospitalizations for respiratory syncytial virus

J Pediatr. 2009 Feb;154(2):296-8. doi: 10.1016/j.jpeds.2008.07.053.

Abstract

This study used 459 prospectively sampled cord blood samples to examine the association between maternally derived respiratory syncytial virus (RSV)-neutralizing antibodies and the RSV hospitalization season in Denmark. We found a clear temporal association and suggest that RSV-neutralizing antibody level plays a role in the RSV seasonal pattern.

MeSH terms

  • Antibodies, Viral / blood*
  • Denmark / epidemiology
  • Female
  • Hospitalization / statistics & numerical data*
  • Humans
  • Incidence
  • Infant
  • Maternal-Fetal Exchange / immunology
  • Pregnancy
  • Prospective Studies
  • Respiratory Syncytial Virus Infections / epidemiology*
  • Respiratory Syncytial Viruses / immunology*
  • Seasons*

Substances

  • Antibodies, Viral