Seasonal shifts of group A rotavirus strains as a possible mechanism of persistence in the human population

J Med Virol. 2009 Mar;81(3):568-71. doi: 10.1002/jmv.21423.


This article demonstrates how the seasonal predominance of a new rotavirus strain in Asuncion, Paraguay is correlated with a wide spectrum of age groups of children infected in that given season. Therefore, this study provides new evidence to support the idea that seasonal shift of rotavirus strains is a possible mechanism used by the virus to evade herd immunity (acquired by the population due to previous infections) and, thus, ultimately persist in that population.

MeSH terms

  • Child, Preschool
  • Genotype
  • Humans
  • Immunity, Herd
  • Infant
  • Infant, Newborn
  • Paraguay / epidemiology
  • Rotavirus / classification*
  • Rotavirus / immunology
  • Rotavirus / isolation & purification*
  • Rotavirus Infections / epidemiology*
  • Rotavirus Infections / immunology
  • Rotavirus Infections / virology*
  • Seasons*