The Biomolecular Crystallization Database Version 4: expanded content and new features

Acta Crystallogr D Biol Crystallogr. 2009 Jan;65(Pt 1):18-23. doi: 10.1107/S0907444908035440. Epub 2008 Dec 18.


The Biological Macromolecular Crystallization Database (BMCD) has been a publicly available resource since 1988, providing a curated archive of information on crystal growth for proteins and other biological macromolecules. The BMCD content has recently been expanded to include 14 372 crystal entries. The resource continues to be freely available at In addition, the software has been adapted to support the Java-based Lucene query language, enabling detailed searching over specific parameters, and explicit search of parameter ranges is offered for five numeric variables. Extensive tools have been developed for import and handling of data from the RCSB Protein Data Bank. The updated BMCD is called version 4.02 or BMCD4. BMCD4 entries have been expanded to include macromolecule sequence, enabling more elaborate analysis of relations among protein properties, crystal-growth conditions and the geometric and diffraction properties of the crystals. The BMCD version 4.02 contains greatly expanded content and enhanced search capabilities to facilitate scientific analysis and design of crystal-growth strategies.

MeSH terms

  • Animals
  • Crystallization
  • Crystallography, X-Ray
  • Database Management Systems
  • Databases, Protein*
  • Humans
  • Multiprotein Complexes / chemistry*
  • Programming Languages
  • Proteins / chemistry*


  • Multiprotein Complexes
  • Proteins