Radiation dose to patients from radiopharmaceuticals. Addendum 3 to ICRP Publication 53. ICRP Publication 106. Approved by the Commission in October 2007

Ann ICRP. 2008;38(1-2):1-197. doi: 10.1016/j.icrp.2008.08.003.


In this report, the Commission provides biokinetic and dosimetric models for 33 radiopharmaceuticals, as well as recommendations related to breast feeding for mothers who have undergone a nuclear medicine investigation. The report is based on Addenda 3-9 to Publication 53. Addenda 3-7 have been available on the ICRP website (www.icrp.org) as interim reports. The work has been carried out by a Joint Task Group of ICRP Committees 2 and 3. This publication provides biokinetic models, absorbed doses, and effective doses for the following radiopharmaceuticals: 11C-acetate; 11C-amino acids; 11C-brain receptor substances; 11C-methionine; 18F-amino acids; 18F-FET; 18F-FDG; 111In-monoclonal antibodies/fragments; 123I-fatty acids (BMIPP, IPPA); 123I-monoclonal antibodies/fragments; 131I-monoclonal antibodies/fragments; and 201Tl-ion. The publication also provides realistic maximum models for 11C- and 18F-substances, for which no specific models are available.

MeSH terms

  • Antibodies, Monoclonal / chemistry
  • Breast Feeding
  • Female
  • Humans
  • Kinetics
  • Male
  • Maternal Exposure
  • Pregnancy
  • Radiation Protection / methods*
  • Radiometry / methods*
  • Radiometry / standards*
  • Radiopharmaceuticals / therapeutic use*
  • Tissue Distribution


  • Antibodies, Monoclonal
  • Radiopharmaceuticals