[Saccharomyces cerevisiae fungemia associated with multifocal pneumonia in a patient with alcohol-related hepatic cirrhosis]

Infez Med. 2008 Dec;16(4):227-9.
[Article in Italian]

Abstract

Saccharomyces cerevisiae is usually considered non-pathogenic and has rarely been reported as a cause of fungemia in immunocompromised patients, especially those admitted to an intensive care unit or those affected by acquired immune deficiency syndrome or under immunosuppressive treatment. In all described cases the use of probiotic yeast has been given as the main risk factor. We report a case of S. cerevisiae sepsis complicated by pneumonia in a patient affected by alcohol-related cirrhosis with no evidence of probiotic drug intake. In this case recovery was obtained after a treatment course with liposomal amphotericin B. S. cerevisiae should be taken into consideration when sepsis lacks to isolate any aetiological agent.

Publication types

  • Case Reports

MeSH terms

  • Amphotericin B / therapeutic use
  • Antifungal Agents / therapeutic use*
  • Drug Therapy, Combination
  • Fluconazole / therapeutic use
  • Humans
  • Immunocompromised Host*
  • Itraconazole / therapeutic use
  • Liver Cirrhosis, Alcoholic / complications*
  • Liver Cirrhosis, Alcoholic / diagnostic imaging
  • Liver Cirrhosis, Alcoholic / drug therapy
  • Liver Cirrhosis, Alcoholic / microbiology
  • Lung Diseases, Fungal / complications*
  • Lung Diseases, Fungal / diagnostic imaging
  • Lung Diseases, Fungal / drug therapy
  • Male
  • Middle Aged
  • Pyrimidines / therapeutic use
  • Radiography
  • Saccharomyces cerevisiae / isolation & purification*
  • Treatment Outcome
  • Triazoles / therapeutic use
  • Voriconazole

Substances

  • Antifungal Agents
  • Pyrimidines
  • Triazoles
  • Itraconazole
  • Amphotericin B
  • Fluconazole
  • Voriconazole