A neural amplifier with high programmable gain and tunable bandwidth

Gayatri E Perlin; Amir M Sodagar; Kensall D Wise

doi:10.1109/IEMBS.2008.4649873

A neural amplifier with high programmable gain and tunable bandwidth

Annu Int Conf IEEE Eng Med Biol Soc. 2008:2008:3154-7. doi: 10.1109/IEMBS.2008.4649873.

Authors

Gayatri E Perlin¹, Amir M Sodagar, Kensall D Wise

Affiliation

¹ Engineering Research Center for Wireless Integrated MicroSystems (WIMS ERC), Department of Electrical Engineering and Computer Science, University of Michigan, Ann Arbor, MI 48109, USA. geadara@umich.edu

PMID: 19163376
DOI: 10.1109/IEMBS.2008.4649873

Abstract

A neural recording amplifier having programmable gain and bandwidth is presented. The gain can be digitally programmed using 6 bits from 100x to 1100x in steps of 100x. The low-frequency cutoff can be varied from less than 10Hz to above 100Hz to accept or reject field potentials while the high-frequency cutoff is fixed at 9kHz. The input referred noise of this amplifier is 4.8microV(rms) and it consumes 50microW operating from +/-1.5V. Implemented in a 0.5microm technology, the amplifier occupies an area of 0.098mm(2). This amplifier has been successfully demonstrated in-vivo and compared to a commercial amplifier.

Publication types

Research Support, N.I.H., Extramural
Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

Algorithms
Amplifiers, Electronic*
Electric Stimulation / instrumentation*
Electric Stimulation / methods
Electrodes
Electrodes, Implanted
Equipment Design
Humans
Microelectrodes
Models, Theoretical
Nerve Net*
Neurons / pathology

Grants and funding

HHSN265200423631C/PHS HHS/United States