Understanding the words of chromatin regulation

Cell. 2009 Jan 23;136(2):200-6. doi: 10.1016/j.cell.2009.01.009.


Recent studies indicate that chromatin regulatory complexes produce biological specificity in the way that letters produce meanings by combinations into words. Combinatorial assembly of chromatin regulatory complexes may be critical for maximizing the information content provided by arrays of histone modifications.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Chromatin Assembly and Disassembly*
  • Chromosomal Proteins, Non-Histone / metabolism
  • Gene Expression Regulation*
  • Histone Code
  • Humans
  • Vertebrates / genetics


  • Chromosomal Proteins, Non-Histone