Expression analysis of phytohormone-regulated microRNAs in rice, implying their regulation roles in plant hormone signaling

FEBS Lett. 2009 Feb 18;583(4):723-8. doi: 10.1016/j.febslet.2009.01.020. Epub 2009 Jan 22.


Twenty-two conserved miRNAs were chosen to investigate the expression pattern in response to phytohormone treatments, in which the effects of five classic plant hormone stresses were surveyed in Oryza sativa. The results showed that 11 miRNAs were found to be dysregulated by one or more phytohormone treatments. The target genes of these miRNAs were validated in vivo and their expression profiling were revealed. We also analyzed the promoter regions of the 22 conserved miRNAs for phytohormone-responsive elements and the existence of the elements provided further evidences supporting our results. These findings enable us to further investigate the role of miRNAs in phytohormone signaling.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gene Expression Profiling
  • Gene Expression Regulation, Plant*
  • Genes, Plant
  • MicroRNAs / genetics*
  • MicroRNAs / metabolism
  • Oryza / genetics*
  • Oryza / metabolism
  • Plant Growth Regulators / genetics*
  • Plant Growth Regulators / metabolism
  • Promoter Regions, Genetic
  • RNA, Plant / genetics
  • RNA, Plant / isolation & purification
  • Signal Transduction / genetics*


  • MicroRNAs
  • Plant Growth Regulators
  • RNA, Plant