Exploiting the divergent reactivity of aryl-palladium intermediates for the rapid assembly of fluorene and phenanthrene derivatives

Angew Chem Int Ed Engl. 2009;48(10):1849-52. doi: 10.1002/anie.200805780.

Abstract

They all fall down: The value of domino processes can be greatly enhanced when the possibility exists for one to selectively diverge from a common intermediate. In preliminary studies the dual reactivity of aryl-palladium intermediates is exploited. A diverse array of fluorene and phenanthrene derivatives were synthesized in a rapid and efficient manner (see scheme).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Catalysis
  • Fluorenes / chemical synthesis
  • Fluorenes / chemistry*
  • Palladium / chemistry*
  • Phenanthrenes / chemical synthesis
  • Phenanthrenes / chemistry*
  • Stereoisomerism

Substances

  • Fluorenes
  • Phenanthrenes
  • Palladium