Metabolic effects of low glycaemic index diets

Nutr J. 2009 Jan 29:8:5. doi: 10.1186/1475-2891-8-5.


The persistence of an epidemic of obesity and type 2 diabetes suggests that new nutritional strategies are needed if the epidemic is to be overcome. A promising nutritional approach suggested by this thematic review is metabolic effect of low glycaemic-index diet. The currently available scientific literature shows that low glycaemic-index diets acutely induce a number of favorable effects, such as a rapid weight loss, decrease of fasting glucose and insulin levels, reduction of circulating triglyceride levels and improvement of blood pressure. The long-term effect of the combination of these changes is at present not known. Based on associations between these metabolic parameters and risk of cardiovascular disease, further controlled studies on low-GI diet and metabolic disease are needed.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Blood Glucose / metabolism*
  • Cardiovascular Diseases / etiology
  • Diet*
  • Glycemic Index*
  • Insulin / metabolism
  • Insulin Resistance / physiology
  • Insulin Secretion
  • Metabolic Syndrome / prevention & control
  • Obesity / blood
  • Obesity / diet therapy
  • Risk Factors
  • Weight Loss


  • Blood Glucose
  • Insulin