The aim of this study was analysis of kind of interactions between Fe and the other metals: Al, Ba, Ca, Cr, Cu, Mg, Mn, Zn, K i Na in pharyngeal tonsils from girls and boys in several group of age (2-5 years, 6-9 years and 10-15 years) exposed and no exposed to tobacco smoking. This study showed that the kind of interaction dependent on sex, age and exposed to ETS.