Enteroviruses in Patients With Acute Encephalitis, Uttar Pradesh, India

Emerg Infect Dis. 2009 Feb;15(2):295-8. doi: 10.3201/eid1502.080865.

Abstract

An outbreak of viral encephalitis occurred in northern India in 2006. Attempts to identify an etiologic agent in cerebrospinal fluid by using reverse transcription-PCR showed positivity to enterovirus (EV) in 66 (21.6%) of 306 patients. Sequencing and phylogenetic analyses of PCR products from 59 (89.3%) of 66 specimens showed similarity with EV-89 and EV-76 sequences.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acute Disease
  • Adolescent
  • Animals
  • Cell Line
  • Cell Line, Tumor
  • Cerebrospinal Fluid / virology*
  • Child
  • Child, Preschool
  • Cricetinae
  • Disease Outbreaks*
  • Encephalitis, Viral* / diagnosis
  • Encephalitis, Viral* / epidemiology
  • Encephalitis, Viral* / virology
  • Enterovirus Infections / diagnosis
  • Enterovirus Infections / epidemiology
  • Enterovirus Infections / virology
  • Enterovirus* / classification
  • Enterovirus* / genetics
  • Enterovirus* / isolation & purification
  • Humans
  • India / epidemiology
  • Infant
  • Infant, Newborn
  • Phylogeny
  • RNA, Viral / analysis
  • RNA, Viral / isolation & purification
  • Reverse Transcriptase Polymerase Chain Reaction
  • Sequence Analysis, DNA

Substances

  • RNA, Viral