Risk factors for type 2 diabetes in a sixth- grade multiracial cohort: the HEALTHY study

Diabetes Care. 2009 May;32(5):953-5. doi: 10.2337/dc08-1774. Epub 2009 Feb 5.


Objective: HEALTHY is a 3-year middle school intervention program designed to reduce risk factors for type 2 diabetes. The prevalence of diabetes risk factors at baseline in a cohort of 6,358 sixth-grade students is reported.

Research design and methods: Forty-two schools at seven U.S. sites were randomly assigned to intervention or control. Students participated in baseline data collection during fall of 2006.

Results: Overall, 49.3% of children had BMI >or=85th percentile, 16.0% had fasting blood glucose >or=100 mg/dl (<1% had fasting blood glucose >or=126 mg/dl), and 6.8% had fasting insulin >or=30 microU/ml. Hispanic youth were more likely to have BMI, glucose, and insulin levels above these thresholds than blacks and whites.

Conclusions: Sixth-grade students in schools with large minority populations have high levels of risk factors for type 2 diabetes. The HEALTHY intervention was designed to modify these risk factors to reduce diabetes incidence.

Publication types

  • Multicenter Study
  • Research Support, N.I.H., Extramural

MeSH terms

  • Adolescent
  • African Continental Ancestry Group / statistics & numerical data
  • Blood Glucose / analysis
  • Body Mass Index
  • Child
  • Cohort Studies
  • Continental Population Groups
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Diabetes Mellitus, Type 2 / genetics
  • European Continental Ancestry Group / statistics & numerical data
  • Fasting
  • Female
  • Humans
  • Insulin / blood
  • Male
  • Nuclear Family
  • Overweight / epidemiology*
  • Puberty / physiology
  • Randomized Controlled Trials as Topic
  • Risk Factors
  • United States / epidemiology


  • Blood Glucose
  • Insulin