Prevention strategies for healthcare-associated pneumonia

Semin Respir Crit Care Med. 2009 Feb;30(1):86-91. doi: 10.1055/s-0028-1119812. Epub 2009 Feb 6.


Healthcare-associated pneumonia (HCAP) represents one of the largest subsets of patients with pneumonia. Based on epidemiological projections for the aging U.S. population, the number of hospitalizations for HCAP is expected to increase exponentially for the next several decades. The unique risk factors for colonization with resistant pathogens in these patients provide multiple opportunities for HCAP prevention. However, our current understanding of the most effective prevention measures is woefully inadequate and constitutes an extrapolation from studies done in community-acquired and hospital-acquired pneumonia patients. This review explores common prevention strategies that may be applicable to HCAP, highlights areas of controversy that require further study, and describes several areas of ongoing novel investigation.

Publication types

  • Review

MeSH terms

  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use
  • Comorbidity
  • Cross Infection / epidemiology
  • Cross Infection / microbiology
  • Cross Infection / prevention & control*
  • Drug Resistance, Multiple, Bacterial
  • Humans
  • Infection Control*
  • Nutrition Therapy / methods
  • Pneumonia / epidemiology
  • Pneumonia / microbiology
  • Pneumonia / prevention & control*
  • Respiratory Aspiration / prevention & control
  • Vaccination


  • Angiotensin-Converting Enzyme Inhibitors