Sternoclavicular pustulotic osteitis (SAPHO). 20-year interval between skin and bone lesions

J Rheumatol. 1991 Jul;18(7):1104-8.


In 2 cases of palmoplantar pustulosis, a 20-year interval was observed between the skin lesion and the bone involvement. In one case, the bone lesion came first. In the other a skin lesion was seen for 3 weeks without subsequent relapse. The 2 cases underline the multifaceted presentation of the condition for which we have coined the name synovitis acne pustulosis hyperostosis osteitis (SAPHO) syndrome.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Female
  • Humans
  • Middle Aged
  • Osteitis / complications*
  • Osteitis / diagnostic imaging
  • Psoriasis / complications*
  • Psoriasis / pathology
  • Radiography
  • Sternoclavicular Joint*
  • Syndrome
  • Time Factors