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Case Reports
. 2009 Mar;39(3):386-8.
doi: 10.1002/mus.21171.

Response to Methotrexate in a Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patient

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Case Reports

Response to Methotrexate in a Chronic Inflammatory Demyelinating Polyradiculoneuropathy Patient

Jordi Díaz-Manera et al. Muscle Nerve. .

Abstract

We report a patient with chronic inflammatory demyelinating polyradiculoneuropathy and progressive resistance to standard treatment who showed a striking response to methotrexate, 20 mg/week. The improvement, which started 5 months after initiation of therapy, was consistent and permanent. It allowed the previously wheelchair-dependent patient to achieve pharmacological remission. The 2-year follow-up of this case further illustrates the role that methotrexate may play as a treatment option for CIDP patients.

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