Abstract
PFAPA syndrome (periodic fever, aphthous stomatitis, pharyngitis, adenitis) is a benign sporadic syndrome of unknown cause. We report 2 siblings diagnosed with this syndrome. The second case started crisis simultaneously with recurrence of crisis after a 3-year free interval in her brother. This temporal relation suggests environmental factor acting in genetically predisposed children.
MeSH terms
-
Child
-
Child, Preschool
-
Female
-
Fever of Unknown Origin / complications*
-
Fever of Unknown Origin / drug therapy
-
Glucocorticoids / therapeutic use
-
Humans
-
Lymphadenitis* / complications
-
Lymphadenitis* / diagnosis
-
Lymphadenitis* / drug therapy
-
Male
-
Periodicity*
-
Pharyngitis* / complications
-
Pharyngitis* / diagnosis
-
Pharyngitis* / drug therapy
-
Prednisone / therapeutic use
-
Siblings*
-
Stomatitis, Aphthous / complications
-
Stomatitis, Aphthous / diagnosis
-
Stomatitis, Aphthous / drug therapy
-
Syndrome
Substances
-
Glucocorticoids
-
Prednisone