Energy Restriction for Breast Cancer Prevention

Recent Results Cancer Res. 2009;181:97-111. doi: 10.1007/978-3-540-69297-3_11.


Weight gain in adult life is an important risk factor for breast cancer. Observational studies indicate that pre- or postmeno-pausal weight loss is associated with a reduction in risk of postmenopausal breast cancer. Here we summarise lifestyle changes including continuous or intermittent energy restriction and/or exercise which may be beneficial for preventing breast cancer and also potential pharmacological approaches to prevention using energy restriction mimetic agents (ERMAs).

Publication types

  • Review

MeSH terms

  • Breast Neoplasms / metabolism
  • Breast Neoplasms / prevention & control*
  • Caloric Restriction*
  • Energy Metabolism / physiology*
  • Exercise Therapy*
  • Female
  • Humans