Sexual risk behavior associated with co-administration of methamphetamine and other drugs in a sample of HIV-positive men who have sex with men

Am J Addict. Jan-Feb 2009;18(1):65-72. doi: 10.1080/10550490802544466.


This study examined the association between sexual risk behavior and co-administration of methamphetamine with other drugs in a sample of 341 HIV-positive MSM. Those who reported methamphetamine co-administration in the past two months (65%) reported significantly more unprotected anal and oral sex and a greater number of casual, anonymous, and paid sex partners in this timeframe compared to men who used methamphetamine alone. Two primary patterns of co-administration were identified: 1) drug combinations motivated by sexual performance and enhancement (eg, methamphetamine, poppers, sildenafil); and 2) "party drug" combinations (eg, methamphetamine, GHB, ketamine). Implications for further research and possible applications to risk-reduction interventions are discussed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Adult
  • Drug Users / psychology*
  • HIV Infections / psychology*
  • Homosexuality, Male*
  • Humans
  • Illicit Drugs
  • Male
  • Methamphetamine / administration & dosage*
  • Methamphetamine / adverse effects
  • Risk-Taking
  • Sexual Behavior*


  • Illicit Drugs
  • Methamphetamine