Thulium:yttrium-aluminium-garnet Laser Prostatectomy in Men With Refractory Urinary Retention

BJU Int. 2009 Aug;104(3):361-4. doi: 10.1111/j.1464-410X.2009.08412.x. Epub 2009 Feb 11.

Abstract

Objective: To evaluate the feasibility and efficacy of thulium:yttrium-aluminium-garnet (YAG) laser prostatectomy in patients with an indwelling transurethral catheter due to recurrent urinary retention secondary to benign prostatic obstruction.

Patients and methods: Preoperative data and postoperative outcome, as well as complications, were recorded in 65 patients with a history of recurrent urinary retention before surgery (group A), who were compared with a group of 143 men with no recurrent urinary retention (group B).

Results: The mean (sd) volume of the prostate was 45.6 (22.5) and 43.1 (24.5) mL in groups A and B, respectively. The respective preoperative prostate-specific antigen levels were 3.6 (7.8) and 2.8 (6.4) ng/mL, the surgical duration 72.4 (28.9) and 65.6 (28.6) min, the mean laser time and energy 32.5 (11.8) min/140.7 (42.1) kJ and 29.4 (11.6) min/117.6 (11.6) kJ, the maximum urinary flow rate after surgery 19.6 (11.2) and 19.1 (9.6) mL/s, and the postvoid residual urine volume 26.7 (36.3) and 20.6 (27.3) mL. Recorded complications were: bleeding, at 3% in group A and 1.4% in group B; urinary tract infection 15.4% and 4.2%; and a second procedure, 3% and 2.3%. Overall, complications were more frequent in group A (P = 0.02).

Conclusion: Thulium:YAG prostatectomy is feasible and effective, even in patients with potentially impaired detrusor function. The long-term durability of these promising results has yet to be confirmed.

Publication types

  • Evaluation Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Chronic Disease
  • Epidemiologic Methods
  • Humans
  • Lasers, Solid-State / adverse effects
  • Lasers, Solid-State / standards
  • Lasers, Solid-State / therapeutic use*
  • Male
  • Middle Aged
  • Postoperative Complications / etiology
  • Prostatectomy / adverse effects
  • Prostatectomy / methods*
  • Prostatectomy / standards
  • Prostatic Hyperplasia / complications
  • Prostatic Hyperplasia / surgery*
  • Thulium / therapeutic use*
  • Treatment Outcome
  • Urinary Retention / etiology
  • Urinary Retention / surgery*

Substances

  • Thulium