Detection of the nasal cycle in daily activity by remote evaluation of nasal sound

Arch Otolaryngol Head Neck Surg. 2009 Feb;135(2):137-42. doi: 10.1001/archoto.2008.537.


Objectives: To detect the nasal cycle in healthy subjects while they were performing their daily activities, using the Odiosoft-Rhino (OR) software program and to investigate the ability of the OR program to perform this procedure.

Design: Prospective analysis.

Setting: Tertiary referral center.

Patients: Twenty healthy adult volunteers.

Interventions: Investigation of the nasal cycles of volunteers by the OR program every 30 minutes over a period of 12 hours on 4 different days in the same week. Each subject performed expiration every 30 minutes into a microphone, and the nasal sounds were recorded separately for each nasal cavity.

Main outcome measures: The OR data collected during 12 hours for 4 days were analyzed for cyclic nasal obstruction.

Results: The nasal sounds were calculated for each of the nasal cavities and a 2000- to 4000-Hz frequency interval was used for evaluation. In all of the individuals investigated in this study, a cyclic change of nasal patency was detected by the OR program. All of the data were calculated to be significantly different for each nasal cavity (P < .05 for all comparisons). Changes of nasal sounds and comparison of the 2 sides demonstrated that the total amount of cyclic changes ranged between 30 minutes and 2 to 2.5 hours.

Conclusions: With the help of the OR program, we detected the nasal cycles in all of the volunteers, and the periods were not less than 30 minutes or more than 2.5 hours. Because the data collection period was long and the patient compliance was maximal, we believe that the results in the study are more reliable and natural.

MeSH terms

  • Adult
  • Female
  • Humans
  • Male
  • Nasal Cavity / physiology*
  • Patient Compliance
  • Periodicity
  • Prospective Studies
  • Respiratory Physiological Phenomena
  • Software
  • Sound