The failure of HIV vaccines: a new autovaccine may overcome some problems

Med Hypotheses. 2009 Jun;72(6):662-4. doi: 10.1016/j.mehy.2008.12.034. Epub 2009 Feb 14.


The hypothesis of an autovaccine for HIV is borne out by: (1) the present lack of a valid vaccine; (2) by a remarkable improvement of the HAART, which however does not prevent HIV mutagenicity and a consequent valid immunological response and (3) the persistence of a hidden infection ready to thrive again. The preparation of the autovaccine is described as well as the administration schedule but only a clinical study will define its validity.

MeSH terms

  • AIDS Vaccines / biosynthesis*
  • AIDS Vaccines / therapeutic use*
  • Autovaccines / biosynthesis*
  • Autovaccines / therapeutic use*
  • HIV Infections / drug therapy*
  • HIV Infections / prevention & control*
  • Humans


  • AIDS Vaccines
  • Autovaccines