The Structural Dynamics of Macromolecular Processes

Curr Opin Cell Biol. 2009 Feb;21(1):97-108. doi: 10.1016/j.ceb.2009.01.022. Epub 2009 Feb 14.

Abstract

Dynamic processes involving macromolecular complexes are essential to cell function. These processes take place over a wide variety of length scales from nanometers to micrometers, and over time scales from nanoseconds to minutes. As a result, information from a variety of different experimental and computational approaches is required. We review the relevant sources of information and introduce a framework for integrating the data to produce representations of dynamic processes.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.
  • Review

MeSH terms

  • Cell Physiological Phenomena*
  • Computer Simulation
  • Macromolecular Substances / metabolism*
  • Models, Biological

Substances

  • Macromolecular Substances