Association of MCTP2 gene variants with schizophrenia in three independent samples of Scandinavian origin (SCOPE)

Psychiatry Res. 2009 Aug 15;168(3):256-8. doi: 10.1016/j.psychres.2008.08.007. Epub 2009 Feb 15.


The MCTP2 gene is involved in intercellular signal transduction and synapse function. We genotyped 37 tagging SNPs across the MCTP2 gene to study a possible association with schizophrenia in three independent Scandinavian samples. We report, for the first time, a possible involvement of MCTP2 as a potential novel susceptibility gene for schizophrenia.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Female
  • Gene Frequency
  • Genetic Predisposition to Disease*
  • Genome-Wide Association Study
  • Genotype
  • Humans
  • Male
  • Membrane Proteins / genetics*
  • Polymorphism, Single Nucleotide / genetics*
  • Scandinavian and Nordic Countries
  • Schizophrenia / genetics*


  • MCTP2 protein, human
  • Membrane Proteins