A bullous lesion in a neutropenic adolescent

Pediatr Emerg Care. 2009 Feb;25(2):100-1. doi: 10.1097/PEC.0b013e318196fad6.


Ecthyma gangrenosum (EG) is a cutaneous manifestation of bacteremia and has classically been associated with Pseudomonas aeruginosa sepsis. The major risk factor for EG is neutropenia, and it is important to recognize that infectious lesions in neutropenic patients may lack the classic inflammatory features of infection in normal hosts. Ecthyma gangrenosum can be the herald of severe sepsis in neutropenic children.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Blister / drug therapy
  • Blister / immunology
  • Blister / microbiology*
  • Clavulanic Acid / therapeutic use
  • Drug Therapy, Combination
  • Gentamicins / therapeutic use
  • Humans
  • Immunocompromised Host
  • Male
  • Neutropenia / complications*
  • Pseudomonas Infections / diagnosis*
  • Pseudomonas Infections / drug therapy
  • Pseudomonas Infections / immunology
  • Thigh
  • Ticarcillin / therapeutic use


  • Gentamicins
  • Clavulanic Acid
  • Ticarcillin