Serial MR imaging in Creutzfeldt-Jakob disease

Neuroradiology. 1991;33(4):364-7. doi: 10.1007/BF00587828.


Serial magnetic resonance (MR) imagings of two autopsied patients with Creutzfeldt-Jakob disease (CJD) are presented. Both patients showed a dramatic progression of brain atrophy. The initial MR imagings were, however, interpreted as normal except for localized mild cortical atrophy in one patient. When a normal MR image is obtained in a demented middle-aged or aged patient, CJD may still need to be ruled out: follow up MR imaging may be useful.

MeSH terms

  • Aged
  • Brain / pathology*
  • Creutzfeldt-Jakob Syndrome / diagnosis*
  • Creutzfeldt-Jakob Syndrome / pathology
  • Female
  • Humans
  • Magnetic Resonance Imaging*
  • Male
  • Middle Aged