Metabolic enzymes as oncogenes or tumor suppressors

N Engl J Med. 2009 Feb 19;360(8):813-5. doi: 10.1056/NEJMe0810213.
No abstract available

Publication types

  • Comment
  • Editorial

MeSH terms

  • Brain Neoplasms / genetics
  • DNA Mutational Analysis
  • Fumarate Hydratase / genetics
  • Fumarate Hydratase / metabolism
  • Glioblastoma / genetics
  • Glioma / genetics*
  • Humans
  • Hypoxia-Inducible Factor 1 / metabolism*
  • Isocitrate Dehydrogenase / genetics*
  • Isocitrate Dehydrogenase / metabolism
  • Mutation
  • Succinate Dehydrogenase / genetics
  • Succinate Dehydrogenase / metabolism

Substances

  • Hypoxia-Inducible Factor 1
  • Isocitrate Dehydrogenase
  • isocitrate dehydrogenase 2, human
  • Succinate Dehydrogenase
  • Fumarate Hydratase