Bisphosphonate osteonecrosis: a protocol for surgical management

Br J Oral Maxillofac Surg. 2009 Jun;47(4):294-7. doi: 10.1016/j.bjoms.2009.01.007. Epub 2009 Feb 23.

Abstract

We present a protocol for the management of a subgroup of patients with bisphosphonate osteonecrosis who presented with painful, exposed, necrotic, alveolar bone. It is simple and can easily be adapted to suit anatomical variations of the oral cavity. Current guidelines based on consensus for the management of bisphosphonate-induced osteonecrosis fail to provide mucosal coverage, which is a primary requirement in managing the condition. We have evaluated the results of a group of 15 patients and analysed their postoperative progress for 24 months.

MeSH terms

  • Aged
  • Alveolar Bone Loss / surgery
  • Bone Density Conservation Agents / adverse effects*
  • Diphosphonates / adverse effects*
  • Female
  • Follow-Up Studies
  • Humans
  • Jaw Diseases / chemically induced*
  • Jaw Diseases / diagnosis
  • Jaw Diseases / therapy
  • Male
  • Mandibular Diseases / chemically induced
  • Mandibular Diseases / surgery
  • Middle Aged
  • Osteonecrosis / chemically induced*
  • Osteonecrosis / diagnosis
  • Osteonecrosis / therapy
  • Tooth Extraction
  • Treatment Outcome

Substances

  • Bone Density Conservation Agents
  • Diphosphonates