Evaluation of dengue nonstructural protein 1 antigen strip for the rapid diagnosis of patients with dengue infection

Wathanee Chaiyaratana; Ampaiwan Chuansumrit; Viroj Pongthanapisith; Kanchana Tangnararatchakit; Sarapee Lertwongrath; Sutee Yoksan

doi:10.1016/j.diagmicrobio.2009.01.004

Evaluation of dengue nonstructural protein 1 antigen strip for the rapid diagnosis of patients with dengue infection

Diagn Microbiol Infect Dis. 2009 May;64(1):83-4. doi: 10.1016/j.diagmicrobio.2009.01.004. Epub 2009 Feb 18.

Authors

Wathanee Chaiyaratana¹, Ampaiwan Chuansumrit, Viroj Pongthanapisith, Kanchana Tangnararatchakit, Sarapee Lertwongrath, Sutee Yoksan

Affiliation

¹ Research Center, Faculty of Medicine, Ramathibodi Hospital, Bangkok 10400, Thailand. rawcy@mahidol.ac.th

PMID: 19232857
DOI: 10.1016/j.diagmicrobio.2009.01.004

Abstract

Two hundred twenty samples obtained from 104 patients with dengue infection (n = 89) and other febrile illnesses (n = 15) were assayed for dengue nonstructural protein 1 (NS1) antigen by enzyme immunoassay and by an immunochromatography (lateral flow) test strip. The sensitivity and the specificity of dengue NS1 antigen strip were 98.9% and 90.6%, respectively.

Publication types

Comparative Study
Evaluation Study
Research Support, Non-U.S. Gov't

MeSH terms

Antigens, Viral / blood*
Dengue / diagnosis*
Humans
Immunoassay / methods
Reagent Kits, Diagnostic*
Sensitivity and Specificity
Viral Nonstructural Proteins / blood*

Substances

Antigens, Viral
NS1 protein, Dengue virus type 2
NS1 protein, dengue-1 virus
Reagent Kits, Diagnostic
Viral Nonstructural Proteins