The dynamic landscapes of RNA architecture

Cell. 2009 Feb 20;136(4):604-9. doi: 10.1016/j.cell.2009.02.003.


A wealth of information on RNA folding and ribonucleoprotein assembly has emerged from analyses of structures and from the use of innovative biophysical tools. Although integrating data obtained from static structures with dynamic measurements presents major challenges, such efforts are opening new vistas on the RNA folding landscape.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Base Sequence
  • Humans
  • Models, Molecular
  • Molecular Sequence Data
  • Nucleic Acid Conformation
  • RNA / chemistry*
  • Thermodynamics


  • RNA