Turnabout is fair play: T cell stimulation by dendritic cell-expressed CD40L

David F Tough

doi:10.1016/j.immuni.2009.01.002

Turnabout is fair play: T cell stimulation by dendritic cell-expressed CD40L

Immunity. 2009 Feb 20;30(2):171-3. doi: 10.1016/j.immuni.2009.01.002.

Author

David F Tough¹

Affiliation

¹ Immuno-Inflammation Centre of Excellence in Drug Discovery, GlaxoSmithKline, Gunnels Wood Road, Stevenage, UK. david.f.tough@gsk.com

PMID: 19239898
DOI: 10.1016/j.immuni.2009.01.002

Abstract

CD40L expressed on T cells plays an important role in stimulating the function of dendritic cells (DCs). In this issue of Immunity, Johnson et al. (2009) demonstrate a role for DC-expressed CD40L in priming CD8(+) T cell responses.

Publication types

Comment

MeSH terms

Animals
CD40 Ligand / immunology*
CD40 Ligand / metabolism*
Dendritic Cells / immunology*
Dendritic Cells / metabolism*
T-Lymphocytes / immunology*

Substances

CD40 Ligand