First higher-order photocycloaddition to a C=N bond: 1,3-diazepines from maleimides

Kara L Cubbage; Andrew J Orr-Ewing; Kevin I Booker-Milburn

doi:10.1002/anie.200805846

First higher-order photocycloaddition to a C=N bond: 1,3-diazepines from maleimides

Angew Chem Int Ed Engl. 2009;48(14):2514-7. doi: 10.1002/anie.200805846.

Authors

Kara L Cubbage¹, Andrew J Orr-Ewing, Kevin I Booker-Milburn

Affiliation

¹ School of Chemistry, University of Bristol, Cantock's Close, Bristol, BS8 1TS, UK.

PMID: 19248062
DOI: 10.1002/anie.200805846

Abstract

A light touch is all that is required to cleave a maleimide C-N bond to effect a [5+2] photocycloaddition with a sterically encumbered C=N moiety (see scheme).