Microbiology and antimicrobial treatment of orbital and intracranial complications of sinusitis in children and their management

Int J Pediatr Otorhinolaryngol. 2009 Sep;73(9):1183-6. doi: 10.1016/j.ijporl.2009.01.020. Epub 2009 Feb 26.


This review describes the microbiology, and medical management of orbital and intracranial complications of sinusitis in children. The most common complications are orbital cellulitis, subperiosteal abscess, orbital abscess, brain abscess, subdural empyema and meningitis. The predominate organisms recovered from these infection are anaerobic, aerobic, and microaerophilic bacteria of oral flora origin. Establishing the microbiology by obtaining appropriate cultures for both aerobic and anaerobic bacteria are essential for proper antimicrobial selection. Early recognition and appropriate surgical and medical therapy are essential to ensure recovery.

Publication types

  • Review

MeSH terms

  • Abscess / drug therapy
  • Abscess / microbiology*
  • Anti-Bacterial Agents / therapeutic use
  • Cellulitis / drug therapy
  • Cellulitis / microbiology*
  • Central Nervous System Bacterial Infections / drug therapy
  • Central Nervous System Bacterial Infections / microbiology*
  • Child
  • Child, Preschool
  • Humans
  • Orbital Diseases / drug therapy
  • Orbital Diseases / microbiology*
  • Periostitis / drug therapy
  • Periostitis / microbiology*
  • Sinusitis / complications*


  • Anti-Bacterial Agents