Intraoperative performance and postoperative outcomes of cataract surgery in infant eyes with microphthalmos

J Cataract Refract Surg. 2009 Mar;35(3):519-28. doi: 10.1016/j.jcrs.2008.11.031.


Purpose: To report the intraoperative performance and postoperative outcomes in microphthalmic eyes of infants younger than 1 year having bilateral cataract surgery.

Setting: Iladevi Cataract & IOL Research Centre, Ahmedabad, India.

Methods: This prospective observational study excluded eyes with ocular trauma, inflammation, posterior persistent fetal vasculature causing stretching of the ciliary processes or tractional retinal detachment, aniridia, or chorioretinal coloboma. Intraoperative observations included the rate of peripheral extension of the anterior capsule tear, intraoperative iris prolapse/trauma, and posterior capsule tear. All eyes were left aphakic. Postoperative observations included visual outcome, posterior synechias, visual axis obscuration (VAO), and glaucoma.

Results: The study evaluated 42 eyes of 21 infants. The mean age at surgery was 4.0 months +/- 2.6 (SD) and the mean follow-up, 25.6 +/-11.3 months. Surgery was performed using the limbal approach in 30 eyes (71.4%) and by pars plicata lensectomy in 12 eyes (28.6%). In the limbal group, 3 eyes (10.0%) had an incomplete anterior capsulorhexis, 2 eyes (6.7%) had iris trauma, and 2 eyes (6.7%) had peripheral extension of the posterior capsulectomy edge. At the final follow-up, visual acuity remained stable in 4 eyes (9.5%) and was improved in 38 eyes (90.5%). The complications were posterior synechias in 15 eyes (35.7%), glaucoma in 13 eyes (30.9%), and VAO in 7 eyes (16.7%).

Conclusion: The results suggest that good visual outcomes can be obtained in microphthalmic patients with bilateral congenital cataract after early surgical intervention, with an acceptable rate of serious postoperative complications.

MeSH terms

  • Aphakia, Postcataract / etiology
  • Aphakia, Postcataract / physiopathology
  • Aphakia, Postcataract / therapy
  • Cataract / congenital*
  • Cataract Extraction / methods*
  • Contact Lenses
  • Eyeglasses
  • Female
  • Follow-Up Studies
  • Humans
  • Infant
  • Intraoperative Complications
  • Male
  • Microphthalmos / complications
  • Microphthalmos / surgery*
  • Postoperative Complications
  • Prospective Studies
  • Treatment Outcome
  • Visual Acuity / physiology