[Angiotensin (1-7): a new link in the renin-angiotensin-aldosterone system (RAAS)]

Postepy Hig Med Dosw (Online). 2009 Feb 11:63:23-9.
[Article in Polish]

Abstract

The discovery of a new angiotensin-converting enzyme (ACE2) and studies of the biological activity of angiotensin (1-7) indicate the complexity of the functioning of the renin-angiotensinaldosterone system (RAAS). In this paper the activities of angiotensin (1-7) are summarized. Angiotensin (1-7) has vasodilating, antiproliferative, antifibrotic, and antithrombotic properties which antagonize the action of angiotensin II. This indicates new possibilities for the future use of these effects for better treatment efficiency of cardiovascular diseases.

Publication types

  • Review

MeSH terms

  • Angiotensin I / metabolism*
  • Cardiovascular Diseases / physiopathology*
  • Humans
  • Peptide Fragments / metabolism*
  • Renin-Angiotensin System / physiology*

Substances

  • Peptide Fragments
  • Angiotensin I
  • angiotensin I (1-7)