Purpose: To study the pupillary light reflex in patients with choroidal neovascularization due to age-related macular degeneration (AMD).
Methods: The study included 15 patients with AMD and 15 control subjects. A full recording of the pupil's reaction to light was registered and the following eight parameters were measured and reported: baseline pupil (R1), latency (T1), minimum pupil radius (R2), amplitude (AMP), maximum constriction velocity (VCmax), maximum constriction acceleration (ACmax), time for maximum velocity (T2), and time for maximum constriction (T3).
Results: All variables measured presented alterations in the AMD group and a number of them were significantly reduced in the AMD group.
Conclusions: The presence of neovascular AMD significantly affects the pupil's response to light stimulus when compared to normal subjects.