Three-dimensional polarization sensitive OCT imaging and interactive display of the human retina

Opt Express. 2009 Mar 2;17(5):4151-65. doi: 10.1364/oe.17.004151.


Polarization sensitive OCT has recently been shown to provide tissue specific contrast, enabling direct identification of retinal layers based on the intrinsic properties of their interaction with light. However, the capabilities of displaying and analyzing 3D datasets in scientific publications were rather limited. Within the framework of the Interactive Science Publishing project, we present new ways of displaying and analyzing 3D sets of various polarization parameters recorded in healthy and diseased human retinas. These datasets can be interactively explored by the reader. Furthermore, we provide data of the 3D distribution of backscattered Stokes vectors to allow the reader to develop and test their own data processing algorithms.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Algorithms
  • Atrophy
  • Choroid Neoplasms / pathology
  • Choroidal Neovascularization / pathology
  • Databases, Factual
  • Female
  • Fluorescein Angiography
  • Humans
  • Imaging, Three-Dimensional
  • Macular Degeneration / pathology
  • Male
  • Middle Aged
  • Models, Theoretical
  • Nevus / pathology
  • Optical Phenomena
  • Retina / anatomy & histology*
  • Retina / pathology
  • Retinal Pigment Epithelium / pathology
  • Tomography, Optical Coherence / methods*
  • Tomography, Optical Coherence / statistics & numerical data