Wegener's granulomatosis

Middle East J Anaesthesiol. 2009 Feb;20(1):21-9.


The immunopathologic disease, Wegener's granulomatosis, presents a challenge to the anesthesiologist due to multisystem involvement resulting in potential abnormalities of the airway, respiratory, circulatory, renal, and central/peripheral nervous systems. It is a systemic vasculitis of small, medium and occasional large arterial involvement. A familiarity with the proper approach to perioperative management is essential. Additional considerations must be made as problems arise from immunosuppressant and corticosteroid treatment.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Anesthesia, Conduction / methods*
  • Diagnosis, Differential
  • Female
  • Granulomatosis with Polyangiitis* / complications
  • Granulomatosis with Polyangiitis* / diagnosis
  • Granulomatosis with Polyangiitis* / therapy
  • Humans
  • Middle Aged
  • Perioperative Care
  • Respiration, Artificial / methods
  • Tracheostomy / methods