ParaHox cluster evolution--hagfish and beyond

Zoolog Sci. 2008 Oct;25(10):955-9. doi: 10.2108/zsj.25.955.


Abstract The ParaHox genes comprise three Hox-related homeobox gene families, found throughout the animals. They were first discovered in the invertebrate chordate amphioxus, where they are tightly clustered. In this paper we carry out a comparative review of ParaHox gene cluster organization among the deuterostomes, and discuss how the recently published hagfish ParaHox clusters fit into current theories about the evolution of this group of genes.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Cluster Analysis*
  • Genes, Homeobox / genetics*
  • Hagfishes / genetics*
  • Multigene Family*