A false positive F-FDG PET/CT scan caused by breast silicone injection

Korean J Radiol. Mar-Apr 2009;10(2):194-6. doi: 10.3348/kjr.2009.10.2.194. Epub 2009 Mar 3.


We present here the case of a 40-year-old woman with a greater than 10 year prior history of bilateral breast silicone injection and saline bag implantation. Bilateral palpable breast nodules were observed, but the ultrasound scan was suboptimal and the magnetic resonance imaging showed no gadolinium-enhanced tumor. The (18)F-FDG PET/CT scan showed a hypermetabolic nodule in the left breast with a 30% increase of (18)F-FDG uptake on the delayed imaging, and this mimicked breast cancer. She underwent a left partial mastectomy and the pathology demonstrated a siliconoma.

Keywords: 18F-FDG PET/CT; Breast, siliconoma.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Breast Implants / adverse effects
  • Breast Neoplasms / diagnosis
  • Diagnosis, Differential
  • False Positive Reactions*
  • Female
  • Fluorodeoxyglucose F18
  • Granuloma, Foreign-Body / diagnosis*
  • Humans
  • Injections
  • Positron-Emission Tomography*
  • Radiopharmaceuticals
  • Silicones / administration & dosage
  • Silicones / adverse effects*
  • Tomography, X-Ray Computed*


  • Radiopharmaceuticals
  • Silicones
  • Fluorodeoxyglucose F18