Prognostic value of increased adiponectin plasma concentrations in patients with acute destabilized heart failure

Clin Biochem. 2009 Jul;42(10-11):1190-3. doi: 10.1016/j.clinbiochem.2009.02.023. Epub 2009 Mar 6.

Abstract

Objectives: To evaluate the prognostic value of adiponectin in patients with acute destabilized heart failure.

Design and methods: Adiponectin was measured in 137 consecutive heart failure patients attending an emergency department. The endpoint was 1-year all-cause mortality.

Results: In Cox proportional-hazards regression, an adiponectin plasma concentration>24.1 mg/L had a risk ratio of 2.46 (95% CI, 1.24-4.87), independently of classical risk factors and B-type natriuretic peptide.

Conclusions: Adiponectin predicts mortality in patients with acute destabilized heart failure.

MeSH terms

  • Acute Disease
  • Adiponectin / blood*
  • Cohort Studies
  • Heart Failure / blood*
  • Heart Failure / diagnosis*
  • Humans
  • Kaplan-Meier Estimate
  • Prognosis
  • Proportional Hazards Models

Substances

  • Adiponectin