Necrosis and lymphocytic infiltration in choroidal melanomas

Acta Ophthalmol (Copenh). 1991 Jun;69(3):347-51. doi: 10.1111/j.1755-3768.1991.tb04826.x.


Patient survival, tumor lymphocytic infiltration and tumor necrosis were studied and evaluated in 43 enucleated eyes with the same histological diagnosis of spindle 'B' malignant melanoma of the choroid. A significant difference (P less than 0.05) was found between the survival rate of melanoma patients with no evidence of lymphocytic infiltration and/or necrosis in the tumor, compared to those with any evidence of of lymphocytic infiltration and/or tumor necrosis.

MeSH terms

  • Choroid Neoplasms / mortality
  • Choroid Neoplasms / pathology*
  • Eye Enucleation
  • Humans
  • Lymphocytes / pathology*
  • Melanoma / mortality
  • Melanoma / pathology*
  • Necrosis
  • Retrospective Studies
  • Survival Rate