Radiological imaging change in a malignant bowel obstruction patient treated with octreotide

Support Care Cancer. 2009 Jun;17(6):753-5. doi: 10.1007/s00520-009-0608-4. Epub 2009 Mar 11.


Introduction: Malignant bowel obstruction (MBO) is a complication in advanced cancer patients with abdominal and pelvic malignancy. Recent research has established the efficacy of octreotide for MBO-related symptom relief. The mechanism that octreotide increases water absorption in case of MBO has not been demonstrated except for experimental animal and normal human model.

Case report: We present a 60-year-old man with pancreatic cancer and MBO treated with octreotide. Radiological imaging showed the disappearance of large-volume fluid retention in the small intestine with alleviating vomiting within 2 days. This radiological change might result from the effect of octreotide increasing water absorption in intestine tract.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Agents, Hormonal / therapeutic use
  • Gastrointestinal Agents / therapeutic use
  • Humans
  • Intestinal Obstruction / diagnostic imaging
  • Intestinal Obstruction / drug therapy*
  • Intestinal Obstruction / etiology
  • Male
  • Middle Aged
  • Octreotide / therapeutic use*
  • Pancreatic Neoplasms / complications*
  • Radiography
  • Vomiting / drug therapy
  • Vomiting / etiology


  • Antineoplastic Agents, Hormonal
  • Gastrointestinal Agents
  • Octreotide