Duodenal mantle cell lymphoma in a patient with advanced sigmoid adenocarcinoma

South Med J. 2009 Apr;102(4):429-31. doi: 10.1097/SMJ.0b013e31819bc4b0.


While colorectal cancer is one of the most commonly encountered gastrointestinal malignancies, primary lymphoma is an uncommon neoplasm of the gastrointestinal tract. The duodenum is not a common location for the recurrence of colon cancer or of primary gastrointestinal lymphoma. Studies regarding mantle cell lymphoma (MCL) as a secondary synchronous or metachronous malignancy are limited. Here we report a patient who received concurrent chemoradiotherapy for his advanced sigmoid adenocarcinoma and developed MCL in the duodenal bulb 20 months later. Suspected lesions should be biopsied and examined for a secondary neoplasm, especially when they appear in an uncommon location for metastasis or direct invasion.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / diagnosis*
  • Adenocarcinoma / pathology
  • Aged
  • Colon, Sigmoid / pathology*
  • Colonic Neoplasms / diagnosis*
  • Colonic Neoplasms / pathology
  • Contrast Media
  • Diagnosis, Differential
  • Duodenum / pathology*
  • Fatal Outcome
  • Humans
  • Lymphoma, Mantle-Cell / diagnosis*
  • Lymphoma, Mantle-Cell / pathology
  • Lymphoma, Mantle-Cell / therapy
  • Male
  • Tomography, X-Ray Computed


  • Contrast Media