Synaptogenic proteins and synaptic organizers: "many hands make light work"

Neuron. 2009 Mar 12;61(5):650-2. doi: 10.1016/j.neuron.2009.02.014.


Synaptogenesis is thought to be mediated by cell adhesion proteins, which induce the initial contact between an axon and its target cell and subsequently recruit and organize the presynaptic and postsynaptic protein machinery required for synaptic transmission. A new study by Linhoff and colleagues in this issue of Neuron identifies adhesion proteins of the LRRTM family as novel synaptic organizers.

Publication types

  • Comment

MeSH terms

  • Animals
  • Nerve Tissue Proteins / genetics
  • Nerve Tissue Proteins / physiology*
  • Neurons / cytology
  • Neurons / physiology*
  • Synapses / physiology*


  • Nerve Tissue Proteins