Signaling aversive events in the midbrain: worse than expected

Neuron. 2009 Mar 12;61(5):655-6. doi: 10.1016/j.neuron.2009.02.016.


Although we know a great deal about how the brain processes information about aversive and appetitive stimuli, it is not clear how these two systems interact to guide behavior. In this issue of Neuron, Jhou and colleagues identify a region in the midbrain tegmentum that signals aversive events and inhibits midbrain dopamine neurons.

Publication types

  • Comment

MeSH terms

  • Animals
  • Avoidance Learning / physiology*
  • Behavior, Animal / physiology
  • Mesencephalon / physiology*
  • Signal Transduction / physiology*