Metastatic uterine adenocarcinoma and hepatic lipomatosis in a llama (Lama glama)

J Vet Diagn Invest. 2009 Mar;21(2):280-2. doi: 10.1177/104063870902100222.

Abstract

A 6-year-old, female llama (Lama glama) presented with progressive anorexia and ascites. Postmortem examination revealed an infiltrative uterine adenocarcinoma with widespread metastases. The neoplasm completely replaced and infiltrated the myometrium of the uterine body and cervix and metastasized largely to the serosal surfaces of the peritoneal cavity. Histopathology identified a highly invasive growth of neoplastic cells in solid packets or tubular arrangements and marked fibroplasia. No bovine or llama papillomavirus DNA was detected intralesionally by polymerase chain reaction.

Publication types

  • Case Reports

MeSH terms

  • Adenocarcinoma / secondary
  • Adenocarcinoma / veterinary*
  • Adenocarcinoma / virology
  • Animals
  • Camelids, New World*
  • DNA, Viral / chemistry
  • DNA, Viral / genetics
  • Fatal Outcome
  • Female
  • Lipomatosis / pathology
  • Lipomatosis / veterinary*
  • Papillomaviridae / genetics
  • Papillomaviridae / isolation & purification*
  • Papillomavirus Infections / veterinary*
  • Papillomavirus Infections / virology
  • Polymerase Chain Reaction / veterinary
  • Uterine Neoplasms / pathology
  • Uterine Neoplasms / veterinary*
  • Uterine Neoplasms / virology
  • Viral Proteins / chemistry
  • Viral Proteins / genetics

Substances

  • DNA, Viral
  • Viral Proteins