Dual role of the oligopeptide permease Opp3 during growth of Staphylococcus aureus in milk

Appl Environ Microbiol. 2009 May;75(10):3355-7. doi: 10.1128/AEM.02819-08. Epub 2009 Mar 13.

Abstract

Staphylococcus aureus RN6390 presents a diauxic growth in milk, due to amino acid limitation. Inactivation of the oligopeptide permease Opp3 (dedicated to the nitrogen nutrition of the strain) not only affects the growth of the strain but also results in reduced expression levels of three major extracellular proteases.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Bacterial Proteins / genetics
  • Bacterial Proteins / metabolism*
  • Colony Count, Microbial
  • Gene Expression Regulation, Bacterial*
  • Membrane Transport Proteins / genetics
  • Membrane Transport Proteins / metabolism*
  • Milk / microbiology*
  • Oligopeptides / metabolism*
  • Staphylococcus aureus / growth & development
  • Staphylococcus aureus / physiology*

Substances

  • Bacterial Proteins
  • Membrane Transport Proteins
  • Oligopeptides
  • oligopeptide permease, Bacteria