Coxofemoral denervation has success rates of 90-96% reported retrospectively for palliative treatment of hip dysplasia. The aim of this study was to objectively evaluate ground reaction forces (GRF) in dysplastic dogs after unilateral denervation. Unilateral coxofemoral denervation was performed by means of a previously reported technique on 10 dogs with asymmetric gait. GRF were measured at zero, one and three months. Statistical analysis was performed using repeated measures analysis of variance and paired t-tests, with p< or =0.05. There was a lack of significant difference in mean peak vertical force (PVF) or vertical impulse (VI) in the operated limb (TX) over time. For the unoperated limb (UnTX), mean PVF and VI significantly decreased over time. The dogs were significantly more lame in the TX limb initially and at one month, however, there was no significant difference between limbs by three months. In the UnTX limb, 40% of dogs decreased PVF by >5%, by three months. Over time, there was no significant difference in mean average rise or mean average fall for TX or UnTX limbs. Between limbs, mean rise in the TX limb was significantly less at zero months, but not at one or three months. Decreased compensatory load shifting to the UnTX limb due to procedural efficacy could explain decreases in the UnTX limb. Worsening disease could also explain decreases in the UnTX limb, and may indicate a protective effect denoted by a lack of change in the TX limb. Longer follow-up would be required in improved dogs in order to document continued efficacy.