A mechanism for stochastic decision making by bacteria

Chembiochem. 2009 Apr 17;10(6):974-6. doi: 10.1002/cbic.200800824.


What mechanism underlies the induction of the lac operon? Expression from the lac operon is an all-or-none phenomenon. Recent work by Choi et al. combines single-molecule imaging of gene expression with single-cell induction measurements to develop a stochastic model describing the critical role of single lac-repressor molecules in induction.

MeSH terms

  • Bacteria / cytology*
  • Bacteria / genetics
  • Bacteria / metabolism
  • Lac Operon
  • Membrane Transport Proteins / metabolism
  • Models, Biological
  • Stochastic Processes


  • Membrane Transport Proteins